1alpha-Hydroxyvitamin D5, CAS [[187935-17-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-13692
Artikelname: 1alpha-Hydroxyvitamin D5, CAS [[187935-17-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-13692
Hersteller Artikelnummer: HY-13692
Alternativnummer: MCE-HY-13692-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: CARD-024
1alpha-Hydroxyvitamin D5 (CARD-024) is a vitamin D analog with extremely low hypercalcemic effects. 1alpha-Hydroxyvitamin D5 effectively attenuates the pro-fibrotic response of colonic myofibroblasts to TGFbeta and high-stiffness substrates by inhibiting the expression of alphaSMA, the phosphorylation of FAK, and the gene expression of MLCK and ET-1, while activating the anti-inflammatory pathway of IL-1beta/COX-2. 1alpha-Hydroxyvitamin D5 can be used in research related to intestinal fibrosis associated with Crohns disease[1].
Molekulargewicht: 428.69
CAS Nummer: [187935-17-7]
Formel: C29H48O2
Target-Kategorie: COX,FAK,Interleukin Related,Myosin
Anwendungsbeschreibung: MCE Product type: Reference compound