1alpha-Hydroxyvitamin D5, CAS [[187935-17-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-13692
Supplier Catalog Number:
HY-13692
Alternative Catalog Number:
MCE-HY-13692-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CARD-024
1alpha-Hydroxyvitamin D5 (CARD-024) is a vitamin D analog with extremely low hypercalcemic effects. 1alpha-Hydroxyvitamin D5 effectively attenuates the pro-fibrotic response of colonic myofibroblasts to TGFbeta and high-stiffness substrates by inhibiting the expression of alphaSMA, the phosphorylation of FAK, and the gene expression of MLCK and ET-1, while activating the anti-inflammatory pathway of IL-1beta/COX-2. 1alpha-Hydroxyvitamin D5 can be used in research related to intestinal fibrosis associated with Crohns disease[1].
Molecular Weight:
428.69
CAS Number:
[187935-17-7]
Formula:
C29H48O2
Target:
COX,FAK,Interleukin Related,Myosin
Application Notes:
MCE Product type: Reference compound
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