N-alpha-Tosyl-Lys chloromethyl ketone (hydrochloride), CAS [[4238-41-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: N-alpha-Tosyl-Lys chloromethyl ketone (hydrochloride), CAS [[4238-41-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-137038
• Hersteller Artikelnummer: HY-137038
• Alternativnummer: MCE-HY-137038-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: TLCK (hydrochloride)

Produktbeschreibung

N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride inhibits caspase-3, caspase-6 and caspase-7, with IC50s of 12.0, 54.5 and 19.3 µM, respectively. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride induces apoptosis in cell HL-60, and inhibits the decrease in mitochondrial transmembrane potential during apoptosis[1].

Produkteigenschaften

• Molekulargewicht: 369.31
• CAS Nummer: [4238-41-9]
• Formel: C14H22Cl2N2O3S
• Target-Kategorie: Caspase,Ser/Thr Protease

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound