2-Chloro-ATP (sodium), CAS [[301334-89-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: 2-Chloro-ATP (sodium), CAS [[301334-89-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-137325A
• Hersteller Artikelnummer: HY-137325A
• Alternativnummer: MCE-HY-137325A-1MG,MCE-HY-137325A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP. It is an antagonist of the purinergic P2Y1 receptor and inhibits intracellular calcium mobilization induced by ADP (HY-W010918) in Jurkat cells expressing the human receptor (Ki=2.3 µM). 2-Chloro-ATP sodium is an agonist of the purinergic P2X receptor and induces inward currents in HEK293 cells expressing human bladder smooth muscle or rat PC12 forms of the receptor (EC50=0.5 and 2.5 µM). 2-Chloro-ATP sodium induces relaxation of precontracted guinea pig cecal strips in a concentration-dependent manner. 2-Chloro-ATP sodium has been used to study the substrate specificity of cyclic nucleotide-dependent protein kinases such as protein kinase A (PKA) and PKG.

Produkteigenschaften

• Molekulargewicht: 629.55
• Reinheit: 97.1
• CAS Nummer: [301334-89-4]
• Formel: C10H11ClN5Na4O13P3
• Target-Kategorie: Calcium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound