2-Chloro-ATP (sodium), CAS [[301334-89-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-137325A
Supplier Catalog Number:
HY-137325A
Alternative Catalog Number:
MCE-HY-137325A-1MG,MCE-HY-137325A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP. It is an antagonist of the purinergic P2Y1 receptor and inhibits intracellular calcium mobilization induced by ADP (HY-W010918) in Jurkat cells expressing the human receptor (Ki=2.3 µM). 2-Chloro-ATP sodium is an agonist of the purinergic P2X receptor and induces inward currents in HEK293 cells expressing human bladder smooth muscle or rat PC12 forms of the receptor (EC50=0.5 and 2.5 µM). 2-Chloro-ATP sodium induces relaxation of precontracted guinea pig cecal strips in a concentration-dependent manner. 2-Chloro-ATP sodium has been used to study the substrate specificity of cyclic nucleotide-dependent protein kinases such as protein kinase A (PKA) and PKG.
Molecular Weight:
629.55
Purity:
97.1
CAS Number:
[301334-89-4]
Formula:
C10H11ClN5Na4O13P3
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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