PROTAC BRAF-V600E degrader-1, CAS [[2417296-84-3]]

Produktübersicht

• Artikelname: PROTAC BRAF-V600E degrader-1, CAS [[2417296-84-3]]
• Artikelnummer: MCE-HY-137487
• Hersteller Artikelnummer: HY-137487
• Alternativnummer: MCE-HY-137487-5MG,MCE-HY-137487-1MG,MCE-HY-137487-10MG,MCE-HY-137487-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC BRAF-V600E degrader-1 (compound 23) is a potent PROTAC BRAF-V600E degrader whlie no degradation activity against BRAF-WT. PROTAC BRAF-V600E degrader-1 exhibits Kd values of 2.4 nM and 2 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-1 degrades BRAF-V600E via the ubiquitin-proteasome system (UPS) and inhibits the growth of melanoma cells[1]. (In the molecular structure, target protein ligand: BI-882370 (HY-107779), red part, E3 ubiquitin enzyme ligand: Pomalidomide (HY-10984), blue part, PROTAC linker: G007-LK (HY-12438), black part.

Produkteigenschaften

• Molekulargewicht: 1001.07
• Reinheit: 98.04
• CAS Nummer: [2417296-84-3]
• Formel: C48H54F2N10O10S
• Target-Kategorie: PROTACs,Raf

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound