Bexotegrast, CAS [[2376257-44-0]]

Produktübersicht

• Artikelname: Bexotegrast, CAS [[2376257-44-0]]
• Artikelnummer: MCE-HY-137561
• Hersteller Artikelnummer: HY-137561
• Alternativnummer: MCE-HY-137561-10MMX1ML,MCE-HY-137561-50MG,MCE-HY-137561-25MG,MCE-HY-137561-100MG,MCE-HY-137561-5MG,MCE-HY-137561-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PLN-74809

Produktbeschreibung

Bexotegrast (PLN-74809) is an orally active, potent dual alphavbeta6/alphavbeta1 integrin inhibitor with Kd of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits alphavbeta6- and alphavbeta1-induced TGF-beta activation with IC50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-beta activation in the fibrotic lung[1][2].

Produkteigenschaften

• Molekulargewicht: 492.61
• Reinheit: 99.74
• CAS Nummer: [2376257-44-0]
• Formel: C27H36N6O3
• Target-Kategorie: Integrin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound