RK-582, CAS [[2171388-28-4]]

Produktübersicht

• Artikelname: RK-582, CAS [[2171388-28-4]]
• Artikelnummer: MCE-HY-137849
• Hersteller Artikelnummer: HY-137849
• Alternativnummer: MCE-HY-137849-10MG,MCE-HY-137849-100MG,MCE-HY-137849-25MG,MCE-HY-137849-50MG,MCE-HY-137849-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RK-582 is a tankyrase inhibitor, antitumor agent, and orally bioavailable growth inhibitor, with an IC50 of 36.1 nM against human tankyrase-1 and an IC50 of 39.2 nM against human tankyrase-2. In APC-mutated colorectal cancer cells, the sensitivity to RK-582 correlates with the level of active beta-catenin, while drug resistance associates with PIK3CA mutation. RK-582 can be used for the research of colorectal cancer[1][2].

Produkteigenschaften

• Molekulargewicht: 510.60
• Reinheit: 98.05
• CAS Nummer: [2171388-28-4]
• Formel: C27H35FN6O3
• Target-Kategorie: PARP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound