BSJ-4-116, CAS [[2519823-34-6]]

Produktübersicht

• Artikelname: BSJ-4-116, CAS [[2519823-34-6]]
• Artikelnummer: MCE-HY-139039
• Hersteller Artikelnummer: HY-139039
• Alternativnummer: MCE-HY-139039-10MMX1ML,MCE-HY-139039-100MG,MCE-HY-139039-1MG,MCE-HY-139039-5MG,MCE-HY-139039-10MG,MCE-HY-139039-25MG,MCE-HY-139039-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BSJ-4-116 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. BSJ-4-116 downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). BSJ-4-116 exhibits potent antiproliferative effects, alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib (HY-10162)[1].

Produkteigenschaften

• Molekulargewicht: 837.38
• Reinheit: 99.87
• CAS Nummer: [2519823-34-6]
• Formel: C40H49ClN8O8S
• Target-Kategorie: CDK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound