3-Oxobetulin acetate, CAS [[136587-07-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: 3-Oxobetulin acetate, CAS [[136587-07-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-139090
• Hersteller Artikelnummer: HY-139090
• Alternativnummer: MCE-HY-139090-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 28-O-Acetyl-3-Oxobetulin, 3-oxo-28-O-Acetylbetulin

Produktbeschreibung

3-Oxobetulin acetate (28-O-Acetyl-3-Oxobetulin, 3-oxo-28-O-Acetylbetulin) is a derivative of betulin (HY-N0083), a cholesterol biosynthesis inhibitor. 3-Oxobetulin acetate inhibits the growth of P388 murine lymphocytic leukemia cells (EC50=0.12 µg/mL) and human MCF-7 breast cancer, SF-268 CNS cancer, H460 lung cancer, and KM20L2 colon cancer cells (GI50s=8, 10.6, 5.2, and 12.7 µg/mL), but not BxPC-3 pancreatic cancer cells or DU145 prostate cancer cells (GI50s=>10 µg/mL for both). 3-Oxobetulin acetate inhibits the replication of X4-tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50=13.4 µM). 3-Oxobetulin acetate is also effective against Listeria donovani amastigotes.

Produkteigenschaften

• Molekulargewicht: 482.74
• CAS Nummer: [136587-07-0]
• Formel: C32H50O3
• Target-Kategorie: Bacterial,Drug Derivative,HIV

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound