Simufilam (PTI-125) is an orally active FLNA modulator. Simufilam restores NMDAR signaling and Arc expression. Simufilam inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Abeta42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam can be used for research of Alzheimers disease[1][2][3].
Molekulargewicht:
259.35
Reinheit:
98.08
CAS Nummer:
[1224591-33-6]
Formel:
C15H21N3O
Target-Kategorie:
Amyloid-beta,iGluR,mTOR,Tau Protein
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten