Brophenexin (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin shows neuroprotective activity. Brophenexin prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 µM. Brophenexin protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1].
Molekulargewicht:
330.09
Reinheit:
99.59
CAS Nummer:
[2243506-33-2]
Formel:
C11H19BrCl2N2
Target-Kategorie:
ERK,iGluR,TRP Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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