Brophenexin (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin shows neuroprotective activity. Brophenexin prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 µM. Brophenexin protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1].
Molecular Weight:
330.09
Purity:
99.59
CAS Number:
[2243506-33-2]
Formula:
C11H19BrCl2N2
Target:
ERK,iGluR,TRP Channel
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
