DDC-01-163, CAS [[2140806-84-2]]

Produktübersicht

• Artikelname: DDC-01-163, CAS [[2140806-84-2]]
• Artikelnummer: MCE-HY-139997
• Hersteller Artikelnummer: HY-139997
• Alternativnummer: MCE-HY-139997-100MG,MCE-HY-139997-50MG,MCE-HY-139997-25MG,MCE-HY-139997-10MG,MCE-HY-139997-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DDC-01-163 is an allosteric PROTAC degrader targeting EGFR. DDC-01-163 is dependent on the ubiquitin-proteasome system. DDC-01-163 can selectively inhibit the proliferation of L858R/T790M (L/T) mutant Ba/F3 cells. DDC-01-163 is effective against Osimertinib (HY-15772)-resistant cells with L/T/C797S and L/T/L718Q EGFR mutations. DDC-01-163 exhibits enhanced anti-proliferative activity against L858R/T790M EGFR-Ba/F3 cells when combined with the ATP-site EGFR inhibitor Osimertinib. DDC-01-163 can be used for the study of non-small cell lung cancer[1].

Produkteigenschaften

• Molekulargewicht: 942.05
• Reinheit: 99.05
• CAS Nummer: [2140806-84-2]
• Formel: C49H51N9O9S
• Target-Kategorie: EGFR,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound