Adenophostin A, CAS [[149091-92-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Adenophostin A, CAS [[149091-92-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-142117
• Hersteller Artikelnummer: HY-142117
• Alternativnummer: MCE-HY-142117-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Adenophostin A is an IP3 receptor (inositol 1,4,5-trisphosphate receptors) modulator and Ca2+ releaser, with an IC50 of 1.3 nM, an EC50 of 1.4 nM, and a Ki of 0.18 nM in rats, and an IC50 of 0.95 nM in humans. Adenophostin A activates IP3 receptors, stimulates Ca2+ release from intracellular stores and microsomes, inhibits the binding of [3H]IP3 to plasma membrane receptors, and activates chloride channels. Adenophostin A resists phosphorylation and dephosphorylation by IP3 metabolic enzymes to maintain its activity, and increases cytoplasmic [Ca2+] levels via calcium mobilization from the endoplasmic reticulum of vascular smooth muscle cells. Adenophostin A is applicable to research related to hemorrhagic shock[1][2][3].

Produkteigenschaften

• Molekulargewicht: 669.32
• CAS Nummer: [149091-92-9]
• Formel: C16H26N5O18P3
• Target-Kategorie: Calcium Channel,Chloride Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound