Adenophostin A, CAS [[149091-92-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-142117
Supplier Catalog Number:
HY-142117
Alternative Catalog Number:
MCE-HY-142117-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Adenophostin A is an IP3 receptor (inositol 1,4,5-trisphosphate receptors) modulator and Ca2+ releaser, with an IC50 of 1.3 nM, an EC50 of 1.4 nM, and a Ki of 0.18 nM in rats, and an IC50 of 0.95 nM in humans. Adenophostin A activates IP3 receptors, stimulates Ca2+ release from intracellular stores and microsomes, inhibits the binding of [3H]IP3 to plasma membrane receptors, and activates chloride channels. Adenophostin A resists phosphorylation and dephosphorylation by IP3 metabolic enzymes to maintain its activity, and increases cytoplasmic [Ca2+] levels via calcium mobilization from the endoplasmic reticulum of vascular smooth muscle cells. Adenophostin A is applicable to research related to hemorrhagic shock[1][2][3].
Molecular Weight:
669.32
CAS Number:
[149091-92-9]
Formula:
C16H26N5O18P3
Target:
Calcium Channel,Chloride Channel
Application Notes:
MCE Product type: Reference compound
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