GNF2133 is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0.0062, >50 µM for DYRK1A and GSK3beta, respectively. GNF2133 shows good proliferation potency and efficacy on rat and human primary beta-cell. GNF2133 significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 has the potential for the research of type 1 diabetes[1].
Molekulargewicht:
434.53
Reinheit:
99.67
CAS Nummer:
[2561414-56-8]
Formel:
C24H30N6O2
Target-Kategorie:
DYRK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
