HDAC-IN-27 (dihydrochloride), CAS [[3069831-25-7]]

Artikelnummer: MCE-HY-142690A
Artikelname: HDAC-IN-27 (dihydrochloride), CAS [[3069831-25-7]]
Artikelnummer: MCE-HY-142690A
Hersteller Artikelnummer: HY-142690A
Alternativnummer: MCE-HY-142690A-10MG,MCE-HY-142690A-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
HDAC-IN-27 dihydrochloride (Compound 11h) is a potent, orally active class I HDAC-selective inhibitor with IC50 values ranging from 0.43 to 3.01 nM against HDAC1-3. HDAC-IN-27 dihydrochloride exhibits both in vivo and in vitro antitumor activity. HDAC-IN-27 dihydrochloride demonstrates significant anti-proliferative activity against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). HDAC-IN-27 dihydrochloride can be used for research in acute myeloid leukemia (AML)[1].
Molekulargewicht: 423.34
Reinheit: 99.08
CAS Nummer: [3069831-25-7]
Formel: C20H24Cl2N4O2
Target-Kategorie: Apoptosis,HDAC
Anwendungsbeschreibung: MCE Product type: Reference compound