HDAC-IN-27 (dihydrochloride), CAS [[3069831-25-7]]
Biozol Catalog Number:
MCE-HY-142690A
Supplier Catalog Number:
HY-142690A
Alternative Catalog Number:
MCE-HY-142690A-10MG,MCE-HY-142690A-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC-IN-27 dihydrochloride (Compound 11h) is a potent, orally active class I HDAC-selective inhibitor with IC50 values ranging from 0.43 to 3.01 nM against HDAC1-3. HDAC-IN-27 dihydrochloride exhibits both in vivo and in vitro antitumor activity. HDAC-IN-27 dihydrochloride demonstrates significant anti-proliferative activity against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). HDAC-IN-27 dihydrochloride can be used for research in acute myeloid leukemia (AML)[1].
Molecular Weight:
423.34
Purity:
99.08
CAS Number:
[3069831-25-7]
Formula:
C20H24Cl2N4O2
Target:
Apoptosis,HDAC
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
