Necrocide 1, CAS [[1247028-61-0]]

Produktübersicht

• Artikelname: Necrocide 1, CAS [[1247028-61-0]]
• Artikelnummer: MCE-HY-14307
• Hersteller Artikelnummer: HY-14307
• Alternativnummer: MCE-HY-14307-5MG,MCE-HY-14307-50MG,MCE-HY-14307-25MG,MCE-HY-14307-100MG,MCE-HY-14307-10MMX1ML,MCE-HY-14307-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Necrocide 1, a necrosis by sodium overload (NECSO) inducer, is a selective transient receptor potential melastatin 4 (TRPM4) agonist with an EC50 of 306.3 nM for human TRPM4. Necrocide 1 triggers TRPM4-dependent necrotic cell death through the induction of sodium influx. Necrocide 1 induces hallmarks of immunogenic cell death incurring calreticulin (CALR) exposure, ATP secretion and high mobility group box 1 (HMGB1) release. Necrocide 1 can be used for the study of breast and prostate cancer[1][2][3].

Produkteigenschaften

• Molekulargewicht: 365.47
• Reinheit: 99.55
• CAS Nummer: [1247028-61-0]
• Formel: C23H27NO3
• Target-Kategorie: Eukaryotic Initiation Factor (eIF),Reactive Oxygen Species (ROS),TRP Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound