Encaleret (sodium), CAS [[787584-62-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-14401B
Artikelname: Encaleret (sodium), CAS [[787584-62-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-14401B
Hersteller Artikelnummer: HY-14401B
Alternativnummer: MCE-HY-14401B-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: CLTX-305 (sodium), JTT-305 (sodium), MK-5442 (sodium)
Encaleret (CLTX-305) sodium is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret sodium exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret sodium can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1[1][2].
Molekulargewicht: 536.01
CAS Nummer: [787584-62-7]
Formel: C29H32ClFNNaO4
Target-Kategorie: CaSR,Thyroid Hormone Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound