PP-C8, CAS [[3032108-74-7]]

Produktübersicht

• Artikelname: PP-C8, CAS [[3032108-74-7]]
• Artikelnummer: MCE-HY-144691
• Hersteller Artikelnummer: HY-144691
• Alternativnummer: MCE-HY-144691-25MG,MCE-HY-144691-1MG,MCE-HY-144691-5MG,MCE-HY-144691-10MG,MCE-HY-144691-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PP-C8 is a potent and selective PROTAC CDK12-Cyclin K degrader. PP-C8 induces CDK12-Cyclin K degradation with DC50s of 416 and 412 nM for CDK12 and Cyclin K, respectively. PP-C8 demonstrates profound synergistic antiproliferative effects with PARP inhibitor in triple-negative breast cancer (TNBC)[1].

Produkteigenschaften

• Molekulargewicht: 866.94
• Reinheit: 99.99
• CAS Nummer: [3032108-74-7]
• Formel: C43H51FN12O7
• Target-Kategorie: CDK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1