5-Octyl-alpha-ketoglutarate, CAS [[1616344-00-3]]

Produktübersicht

• Artikelname: 5-Octyl-alpha-ketoglutarate, CAS [[1616344-00-3]]
• Artikelnummer: MCE-HY-145452
• Hersteller Artikelnummer: HY-145452
• Alternativnummer: MCE-HY-145452-1MG,MCE-HY-145452-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 5-Octyl 2-oxopentanedioate

Produktbeschreibung

5-Octyl-alpha-ketoglutarate (5-Octyl 2-oxopentanedioate) is a cell-permeable substrate for lysine demethylase. 5-Octyl-alpha-ketoglutarate is related to protein demethylation, inhibits cell proliferation of wtCRBN expressing cells, and also enhances Lenalidomide (HY-A0003)-induced sensitivity and inhibits myeloma (MM) ) drug resistance of cells. When myeloma (MM) cells undergo glutamine-dependent proliferation, alpha-ketoglutarate increases glutamine catabolism to promote protein demethylation[1].

Produkteigenschaften

• Molekulargewicht: 258.31
• CAS Nummer: [1616344-00-3]
• Formel: C13H22O5
• Target-Kategorie: E1/E2/E3 Enzyme,Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound