5-Octyl-alpha-ketoglutarate, CAS [[1616344-00-3]]

Product Overview

• Article Name: 5-Octyl-alpha-ketoglutarate, CAS [[1616344-00-3]]
• Biozol Catalog Number: MCE-HY-145452
• Supplier Catalog Number: HY-145452
• Alternative Catalog Number: MCE-HY-145452-1MG,MCE-HY-145452-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 5-Octyl 2-oxopentanedioate

Product Description

5-Octyl-alpha-ketoglutarate (5-Octyl 2-oxopentanedioate) is a cell-permeable substrate for lysine demethylase. 5-Octyl-alpha-ketoglutarate is related to protein demethylation, inhibits cell proliferation of wtCRBN expressing cells, and also enhances Lenalidomide (HY-A0003)-induced sensitivity and inhibits myeloma (MM) ) drug resistance of cells. When myeloma (MM) cells undergo glutamine-dependent proliferation, alpha-ketoglutarate increases glutamine catabolism to promote protein demethylation[1].

Product Properties

• Molecular Weight: 258.31
• CAS Number: [1616344-00-3]
• Formula: C13H22O5
• Target: E1/E2/E3 Enzyme,Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound