KL-11743, CAS [[1369452-53-8]]

Produktübersicht

• Artikelname: KL-11743, CAS [[1369452-53-8]]
• Artikelnummer: MCE-HY-145597
• Hersteller Artikelnummer: HY-145597
• Alternativnummer: MCE-HY-145597-10MMX1ML,MCE-HY-145597-100MG,MCE-HY-145597-50MG,MCE-HY-145597-1MG,MCE-HY-145597-10MG,MCE-HY-145597-25MG,MCE-HY-145597-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death. In addition, KL-11743 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis[1][2][3][4].

Produkteigenschaften

• Molekulargewicht: 522.60
• Reinheit: 99.40
• CAS Nummer: [1369452-53-8]
• Formel: C30H30N6O3
• Target-Kategorie: Disulfidptosis,GLUT

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound