MAX-40279 (hemifumarate), CAS [[2388506-43-0]]

Produktübersicht

• Artikelname: MAX-40279 (hemifumarate), CAS [[2388506-43-0]]
• Artikelnummer: MCE-HY-145723B
• Hersteller Artikelnummer: HY-145723B
• Alternativnummer: MCE-HY-145723B-100MG,MCE-HY-145723B-5MG,MCE-HY-145723B-25MG,MCE-HY-145723B-50MG,MCE-HY-145723B-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MAX-40279 hemifumarate is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate is also effective against the FLT3 mutants such as FLT3D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hemifumarate inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hemifumarate can be used for the research of acute myelogenous leukemia (AML)[1][2][3].

Produkteigenschaften

• Molekulargewicht: 554.59
• Reinheit: 99.56
• CAS Nummer: [2388506-43-0]
• Formel: C22H23FN6OS.1/2C4H4O4
• Target-Kategorie: FGFR,FLT3

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound