MAX-40279 (hemifumarate), CAS [[2388506-43-0]]

Product Overview

• Article Name: MAX-40279 (hemifumarate), CAS [[2388506-43-0]]
• Biozol Catalog Number: MCE-HY-145723B
• Supplier Catalog Number: HY-145723B
• Alternative Catalog Number: MCE-HY-145723B-100MG,MCE-HY-145723B-5MG,MCE-HY-145723B-25MG,MCE-HY-145723B-50MG,MCE-HY-145723B-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MAX-40279 hemifumarate is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate is also effective against the FLT3 mutants such as FLT3D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hemifumarate inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hemifumarate can be used for the research of acute myelogenous leukemia (AML)[1][2][3].

Product Properties

• Molecular Weight: 554.59
• Purity: 99.56
• CAS Number: [2388506-43-0]
• Formula: C22H23FN6OS.1/2C4H4O4
• Target: FGFR,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound