AGI-43192, CAS [[2377491-54-6]]

Produktübersicht

• Artikelname: AGI-43192, CAS [[2377491-54-6]]
• Artikelnummer: MCE-HY-145777
• Hersteller Artikelnummer: HY-145777
• Alternativnummer: MCE-HY-145777-10MMX1ML,MCE-HY-145777-5MG,MCE-HY-145777-10MG,MCE-HY-145777-25MG,MCE-HY-145777-100MG,MCE-HY-145777-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AGI-43192 is a potent and orally active inhibitor of methionine adenosyltransferase 2A (MAT2A) that limitedly penetrates the blood-brain barrier. AGI-43192 exhibits inhibitory activitity against MAT2A and S-adenosyl methionine (SAM) in HCT-116 MTAP-null cells with IC50s of 32 and 14 nM. AGI-43192 can significantly inhibit the proliferation of HCT-116 cells and tumor growth. AGI-43192 can be used to study the role of SAM regulation in the central nervous system (CNS) and colon cancer[1].

Produkteigenschaften

• Molekulargewicht: 484.86
• Reinheit: 99.47
• CAS Nummer: [2377491-54-6]
• Formel: C23H16ClF3N6O
• Target-Kategorie: Methionine Adenosyltransferase (MAT)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1