AGI-43192, CAS [[2377491-54-6]]

Product Overview

• Article Name: AGI-43192, CAS [[2377491-54-6]]
• Biozol Catalog Number: MCE-HY-145777
• Supplier Catalog Number: HY-145777
• Alternative Catalog Number: MCE-HY-145777-50MG,MCE-HY-145777-10MG,MCE-HY-145777-5MG,MCE-HY-145777-100MG,MCE-HY-145777-10MMX1ML,MCE-HY-145777-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AGI-43192 is a potent and orally active inhibitor of methionine adenosyltransferase 2A (MAT2A) that limitedly penetrates the blood-brain barrier. AGI-43192 exhibits inhibitory activitity against MAT2A and S-adenosyl methionine (SAM) in HCT-116 MTAP-null cells with IC50s of 32 and 14 nM. AGI-43192 can significantly inhibit the proliferation of HCT-116 cells and tumor growth. AGI-43192 can be used to study the role of SAM regulation in the central nervous system (CNS) and colon cancer[1].

Product Properties

• Molecular Weight: 484.86
• Purity: 99.47
• CAS Number: [2377491-54-6]
• Formula: C23H16ClF3N6O
• Target: Methionine Adenosyltransferase (MAT)

Application Notes

• Application Notes: MCE Product type: Reference compound