FGFR4-IN-8, CAS [[2765240-52-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: FGFR4-IN-8, CAS [[2765240-52-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-145836
• Hersteller Artikelnummer: HY-145836
• Alternativnummer: MCE-HY-145836-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

FGFR4-IN-8 (Compound 7v) is an ATP-competitive, highly selective covalent inhibitor of wild-type and gatekeeper mutant FGFR4. FGFR4-IN-8 exhibits excellent potency against FGFR4, FGFR4V550L, FGFR4V550M and FGFR4C552S with IC50s of 0.5, 0.25, 1.6, 931 nM, respectively. FGFR4-IN-8 exhibits potent antiproliferative activity against Hep3B hepatocellular carcinoma cells with the IC50 value of 29 nM. FGFR4-IN-8 demonstrates modest in vivo antitumor efficacy in nude mice bearing the Huh-7 xenograft model[1].

Produkteigenschaften

• Molekulargewicht: 654.56
• CAS Nummer: [2765240-52-4]
• Formel: C32H34Cl2FN7O3
• Target-Kategorie: FGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1