MRTX-EX185 (formic), CAS [[2988148-70-3]]

Produktübersicht

• Artikelname: MRTX-EX185 (formic), CAS [[2988148-70-3]]
• Artikelnummer: MCE-HY-145962A
• Hersteller Artikelnummer: HY-145962A
• Alternativnummer: MCE-HY-145962A-1MG,MCE-HY-145962A-10MG,MCE-HY-145962A-5MG,MCE-HY-145962A-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MRTX-EX185 formic is a potent KRAS (G12D) inhibitor with an IC50 of 90 nM. MRTX-EX185 formic can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 formic exhibits broad-spectrum binding properties with IC50s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 formic also binds GDP-loaded HRAS. MRTX-EX185 formic can be used to study various RAS-driven tumors (such as pancreatic cancer) [1].

Produkteigenschaften

• Molekulargewicht: 610.68
• Reinheit: 97.32
• CAS Nummer: [2988148-70-3]
• Formel: C34H35FN6O4
• Target-Kategorie: Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound