MRTX-EX185 (formic), CAS [[2988148-70-3]]

Product Overview

• Article Name: MRTX-EX185 (formic), CAS [[2988148-70-3]]
• Biozol Catalog Number: MCE-HY-145962A
• Supplier Catalog Number: HY-145962A
• Alternative Catalog Number: MCE-HY-145962A-1MG,MCE-HY-145962A-10MG,MCE-HY-145962A-5MG,MCE-HY-145962A-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MRTX-EX185 formic is a potent KRAS (G12D) inhibitor with an IC50 of 90 nM. MRTX-EX185 formic can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 formic exhibits broad-spectrum binding properties with IC50s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 formic also binds GDP-loaded HRAS. MRTX-EX185 formic can be used to study various RAS-driven tumors (such as pancreatic cancer) [1].

Product Properties

• Molecular Weight: 610.68
• Purity: 97.32
• CAS Number: [2988148-70-3]
• Formula: C34H35FN6O4
• Target: Ras

Application Notes

• Application Notes: MCE Product type: Reference compound