Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARgamma, with EC50s of 30 nM, 100 nM and 60 nM for PPARgamma1, PPARgamma2, and PPARgamma, respectively, and a Kd of appr 40 nM for PPARgamma, Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).
Molekulargewicht:
473.50
Reinheit:
99.73
CAS Nummer:
[155141-29-0]
Formel:
C22H23N3O7S
Target-Kategorie:
Autophagy,Ferroptosis,PPAR,TRP Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
