p53 Activator 2, CAS [[2338764-89-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-146095
Hersteller Artikelnummer:
HY-146095
Alternativnummer:
MCE-HY-146095-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
p53 Activator 2 (compound 10ah) intercalats into DNA and results in significant DNA double-strand break.p53 Activator 2 increases the expression of p53, p-p53, CDK4, p21 to cause cell cycle arrest at G2/M phase.p53 Activator 2 induce apoptosis and significantly down-regulates the anti-apoptosis proteins Bcl-2, Bcl-xL and the levels of cyclin B1.p53 Activator 2 has anti-proliferation activity against MGC-803 cells, with an IC50 of 1.73 µM. p53 Activator 2 displays potent anticancer efficiency against MGC-803 xenograft tumors models[1].
Molekulargewicht:
363.41
CAS Nummer:
[2338764-89-7]
Formel:
C20H21N5O2
Target-Kategorie:
Apoptosis,DNA/RNA Synthesis,MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound
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