p53 Activator 2, CAS [[2338764-89-7]] Preis auf Anfrage

Product Overview

• Article Name: p53 Activator 2, CAS [[2338764-89-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-146095
• Supplier Catalog Number: HY-146095
• Alternative Catalog Number: MCE-HY-146095-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

p53 Activator 2 (compound 10ah) intercalats into DNA and results in significant DNA double-strand break.p53 Activator 2 increases the expression of p53, p-p53, CDK4, p21 to cause cell cycle arrest at G2/M phase.p53 Activator 2 induce apoptosis and significantly down-regulates the anti-apoptosis proteins Bcl-2, Bcl-xL and the levels of cyclin B1.p53 Activator 2 has anti-proliferation activity against MGC-803 cells, with an IC50 of 1.73 µM. p53 Activator 2 displays potent anticancer efficiency against MGC-803 xenograft tumors models[1].

Product Properties

• Molecular Weight: 363.41
• CAS Number: [2338764-89-7]
• Formula: C20H21N5O2
• Target: Apoptosis,DNA/RNA Synthesis,MDM-2/p53

Application Notes

• Application Notes: MCE Product type: Reference compound