CAY10789, CAS [[123226-28-8]]

Produktübersicht

• Artikelname: CAY10789, CAS [[123226-28-8]]
• Artikelnummer: MCE-HY-147086
• Hersteller Artikelnummer: HY-147086
• Alternativnummer: MCE-HY-147086-1MG,MCE-HY-147086-10MMX1ML,MCE-HY-147086-25MG,MCE-HY-147086-10MG,MCE-HY-147086-100MG,MCE-HY-147086-50MG,MCE-HY-147086-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CAY10789 is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist (IC50=2.80 µM) and GPBAR1 (G-protein-coupled bile acid receptor 1) agonist (EC50=3 µM). CAY10789 significantly reduces the adhesion of U937 cells to HAEC, reduces the expression of TNF-alpha. CAY10789 shows very promising metabolic stability and excellent pharmacokinetics. CAY10789 can be used for the research of colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases[1].

Produkteigenschaften

• Molekulargewicht: 265.31
• Reinheit: 99.84
• CAS Nummer: [123226-28-8]
• Formel: C17H15NO2
• Target-Kategorie: G protein-coupled Bile Acid Receptor 1,Leukotriene Receptor,TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound