CAY10789, CAS [[123226-28-8]]

Product Overview

• Article Name: CAY10789, CAS [[123226-28-8]]
• Biozol Catalog Number: MCE-HY-147086
• Supplier Catalog Number: HY-147086
• Alternative Catalog Number: MCE-HY-147086-1MG,MCE-HY-147086-10MMX1ML,MCE-HY-147086-25MG,MCE-HY-147086-10MG,MCE-HY-147086-100MG,MCE-HY-147086-50MG,MCE-HY-147086-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CAY10789 is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist (IC50=2.80 µM) and GPBAR1 (G-protein-coupled bile acid receptor 1) agonist (EC50=3 µM). CAY10789 significantly reduces the adhesion of U937 cells to HAEC, reduces the expression of TNF-alpha. CAY10789 shows very promising metabolic stability and excellent pharmacokinetics. CAY10789 can be used for the research of colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases[1].

Product Properties

• Molecular Weight: 265.31
• Purity: 99.84
• CAS Number: [123226-28-8]
• Formula: C17H15NO2
• Target: G protein-coupled Bile Acid Receptor 1,Leukotriene Receptor,TNF Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound