SIAIS164018 (hydrochloride)

Artikelnummer: MCE-HY-147219A
Artikelname: SIAIS164018 (hydrochloride)
Artikelnummer: MCE-HY-147219A
Hersteller Artikelnummer: HY-147219A
Alternativnummer: MCE-HY-147219A-5MG,MCE-HY-147219A-1MG,MCE-HY-147219A-10MG,MCE-HY-147219A-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
SIAIS164018 hydrochloride is a PROTAC-based ALK and EGFR degrader, with IC50 value of 2.5 nM and 6.6 nM for ALK and ALK G1202R, respectively. SIAIS164018 hydrochloride strongly inhibits cancer cells migration and invasion, causes G1 cell cycle arrest and induces apoptosis. SIAIS164018 hydrochloride exhibits better property than Brigatinib (HY-12857)[1].
Molekulargewicht: 919.79
Reinheit: 98.06
Formel: C43H49Cl2N10O7P
Target-Kategorie: Anaplastic lymphoma kinase (ALK),Apoptosis,EGFR,PROTACs
Anwendungsbeschreibung: MCE Product type: Reference compound