SIAIS164018 (hydrochloride)

Product Overview

• Article Name: SIAIS164018 (hydrochloride)
• Biozol Catalog Number: MCE-HY-147219A
• Supplier Catalog Number: HY-147219A
• Alternative Catalog Number: MCE-HY-147219A-5MG,MCE-HY-147219A-1MG,MCE-HY-147219A-10MG,MCE-HY-147219A-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SIAIS164018 hydrochloride is a PROTAC-based ALK and EGFR degrader, with IC50 value of 2.5 nM and 6.6 nM for ALK and ALK G1202R, respectively. SIAIS164018 hydrochloride strongly inhibits cancer cells migration and invasion, causes G1 cell cycle arrest and induces apoptosis. SIAIS164018 hydrochloride exhibits better property than Brigatinib (HY-12857)[1].

Product Properties

• Molecular Weight: 919.79
• Purity: 98.06
• Formula: C43H49Cl2N10O7P
• Target: Anaplastic lymphoma kinase (ALK),Apoptosis,EGFR,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound