HR-19011, CAS [[2851820-52-3]]

Produktübersicht

• Artikelname: HR-19011, CAS [[2851820-52-3]]
• Artikelnummer: MCE-HY-147831
• Hersteller Artikelnummer: HY-147831
• Alternativnummer: MCE-HY-147831-25MG,MCE-HY-147831-100MG,MCE-HY-147831-10MMX1ML,MCE-HY-147831-5MG,MCE-HY-147831-10MG,MCE-HY-147831-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HR-19011 is an eIF2alpha phosphorylation activator targeting heme-regulated inhibitor HRI (EIF2AK1). HR-19011 exhibits growth inhibitory activity against K562 cells with an IC50 value of 3.91 µM. HR-19011 inhibits the growth of hematologic malignancies by targeting HRI to activate the integrated stress response via the HRI-eIF2alpha-ATF4 axis. HR-19011 shows good safety in vivo. HR-19011 can be used for research on hematologic malignancies (leukemia)[1][2].

Produkteigenschaften

• Molekulargewicht: 523.43
• Reinheit: 99.64
• CAS Nummer: [2851820-52-3]
• Formel: C25H19F6N3O3
• Target-Kategorie: Epigenetic Reader Domain,Eukaryotic Initiation Factor (eIF)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound