HR-19011, CAS [[2851820-52-3]]

Product Overview

• Article Name: HR-19011, CAS [[2851820-52-3]]
• Biozol Catalog Number: MCE-HY-147831
• Supplier Catalog Number: HY-147831
• Alternative Catalog Number: MCE-HY-147831-25MG,MCE-HY-147831-100MG,MCE-HY-147831-10MMX1ML,MCE-HY-147831-5MG,MCE-HY-147831-10MG,MCE-HY-147831-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

HR-19011 is an eIF2alpha phosphorylation activator targeting heme-regulated inhibitor HRI (EIF2AK1). HR-19011 exhibits growth inhibitory activity against K562 cells with an IC50 value of 3.91 µM. HR-19011 inhibits the growth of hematologic malignancies by targeting HRI to activate the integrated stress response via the HRI-eIF2alpha-ATF4 axis. HR-19011 shows good safety in vivo. HR-19011 can be used for research on hematologic malignancies (leukemia)[1][2].

Product Properties

• Molecular Weight: 523.43
• Purity: 99.64
• CAS Number: [2851820-52-3]
• Formula: C25H19F6N3O3
• Target: Epigenetic Reader Domain,Eukaryotic Initiation Factor (eIF)

Application Notes

• Application Notes: MCE Product type: Reference compound