PDE1-IN-4, CAS [[3031349-98-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: PDE1-IN-4, CAS [[3031349-98-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-147946
• Hersteller Artikelnummer: HY-147946
• Alternativnummer: MCE-HY-147946-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PDE1-IN-4 (compound 2g) is a potent and selective PDE1 (phosphodiesterase-1) inhibitor, with IC50 values of 10, 145, and 354 nM for PDE1C, PDE1A, and PDE1B, respectively. PDE1-IN-4 inhibits myofibroblast differentiation of human lung fibroblasts induced by TGF-beta1. PDE1-IN-4 shows anti-fibrosis effects through the regulation of cAMP (3',5'-cyclic adenosine monophosphate) and cGMP (3',5'-cyclic guanosine monophosphate). PDE1-IN-4 can be used for idiopathic pulmonary fibrosis (IPF) research[1].

Produkteigenschaften

• Molekulargewicht: 535.63
• CAS Nummer: [3031349-98-8]
• Formel: C33H33N3O4
• Target-Kategorie: Calcium Channel,Phosphodiesterase (PDE)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound