Setidegrasib, CAS [[2821793-99-9]]

Produktübersicht

• Artikelname: Setidegrasib, CAS [[2821793-99-9]]
• Artikelnummer: MCE-HY-148273
• Hersteller Artikelnummer: HY-148273
• Alternativnummer: MCE-HY-148273-10MG,MCE-HY-148273-5MG,MCE-HY-148273-25MG,MCE-HY-148273-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: ASP-3082, KRAS G12D inhibitor 17

Produktbeschreibung

Setidegrasib (KRAS G12D inhibitor 17, ASP3082) is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib suppresses p-ERK, p-AKT, p-S6 levels in AsPC-1 cells. Setidegrasib exhibits anti-tumor activity in various cancer xenograft models in mice. Setidegrasib can be used for the study of KRAS(G12D)-mutated solid tumors. (Blue: VHL ligase ligand (HY-168699), Black: linker (HY-168698), Pink: G12D ligand (HY-168700))[1][2].

Produkteigenschaften

• Molekulargewicht: 1117.30
• Reinheit: 99.65
• CAS Nummer: [2821793-99-9]
• Formel: C60H65FN12O7S
• Target-Kategorie: Akt,ERK,PROTACs,Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound