KTX-951, CAS [[2573298-36-7]]

Produktübersicht

• Artikelname: KTX-951, CAS [[2573298-36-7]]
• Artikelnummer: MCE-HY-148290
• Hersteller Artikelnummer: HY-148290
• Alternativnummer: MCE-HY-148290-25MG,MCE-HY-148290-1MG,MCE-HY-148290-10MG,MCE-HY-148290-10MMX1ML,MCE-HY-148290-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KTX-951 is an orally active IRAK4 and IMiD (Ikaros/Aiolos) substrates PROTAC degrader (Kd = 3.5 nM). KTX-951 has DC50s of 13 nM, 14 nM and 13 nM for IRAK4, Ikaros and Aiolos, respectively. KTX-951 has IC50 of 35 nM for OCl-Ly10 CTG. KTX-951 has antitumor activity.(Pink: IRAK4 ligand-12 (HY-48932), Black: Linker (HY-W382009), Blue: CRBN Ligand Pomalidomide (HY-10984))[1].

Produkteigenschaften

• Molekulargewicht: 850.95
• Reinheit: 99.60
• CAS Nummer: [2573298-36-7]
• Formel: C46H52F2N8O6
• Target-Kategorie: IRAK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound