NecroIr2

Produktübersicht

• Artikelname: NecroIr2
• Artikelnummer: MCE-HY-148366
• Hersteller Artikelnummer: HY-148366
• Alternativnummer: MCE-HY-148366-50MG,MCE-HY-148366-10MG,MCE-HY-148366-100MG,MCE-HY-148366-10MMX1ML,MCE-HY-148366-5MG,MCE-HY-148366-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NecroIr2 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr2 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and regulates CDK4 expression[1].

Produkteigenschaften

• Molekulargewicht: 926.44
• Reinheit: 98.99
• Formel: C46H30ClIrN6O2
• Target-Kategorie: CDK,Mixed Lineage Kinase,RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound