eIF4A3-IN-18, CAS [[1402931-84-3]]

Artikelnummer: MCE-HY-148452
Artikelname: eIF4A3-IN-18, CAS [[1402931-84-3]]
Artikelnummer: MCE-HY-148452
Hersteller Artikelnummer: HY-148452
Alternativnummer: MCE-HY-148452-1MG,MCE-HY-148452-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
eIF4A3-IN-18 (compound 74) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis[1].
Molekulargewicht: 500.54
Reinheit: 99.58
CAS Nummer: [1402931-84-3]
Formel: C29H28N2O6
Target-Kategorie: Eukaryotic Initiation Factor (eIF)
Anwendungsbeschreibung: MCE Product type: Reference compound