Bleximenib (JNJ-75276617) is an orally active and selective menin-KMT2A inhibitor, with IC50 values of 0.1 nM, 0.045 nM, and 0.066 nM for humans, mice, and dogs, respectively. Bleximenib can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib can be used in the research of tumors such as leukemia[1][2].
Molekulargewicht:
599.78
Reinheit:
99.36
CAS Nummer:
[2654081-35-1]
Formel:
C32H50FN7O3
Target-Kategorie:
Apoptosis,FLT3,Histone Methyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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