Bleximenib (JNJ-75276617) is an orally active and selective menin-KMT2A inhibitor, with IC50 values of 0.1 nM, 0.045 nM, and 0.066 nM for humans, mice, and dogs, respectively. Bleximenib can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib can be used in the research of tumors such as leukemia[1][2].
Molecular Weight:
599.78
Purity:
99.36
CAS Number:
[2654081-35-1]
Formula:
C32H50FN7O3
Target:
Apoptosis,FLT3,Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
