Risvodetinib (IkT-148009) is an orally active, selective and brain-penetrant protein tyrosine kinase inhibitor, displaying excellent target efficacy against c-Abl1, c-Abl2/Arg with IC50 values of 33 nM, 14 nM, respectively. Risvodetinib suppresses c-Abl activation and substantially protects dopaminergic neurons from degeneration in mouse models of both inherited and sporadic Parkinsons disease (PD), which is promising for research in the field of PD[1][2][3][4].
Molekulargewicht:
574.68
Reinheit:
99.21
CAS Nummer:
[2031185-00-7]
Formel:
C33H34N8O2
Target-Kategorie:
Bcr-Abl,c-Met/HGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
