E722-2648 is an inhibitor targeting the BCL9 and beta-catenin complex with antitumor activity. E722-2648 blocks complex formation by disrupting the interaction between the two proteins, thereby inhibiting beta-catenin-mediated transcriptional activity and downregulating the expression of WNT target genes. E722-2648 effectively inhibits tumor growth in colon cancer xenograft models and colorectal cancer mouse models. E722-2648 can be used for the research of colon cancer and colorectal cancer[1][2].
Molekulargewicht:
390.61
CAS Nummer:
[931963-55-2]
Formel:
C21H30N2OS2
Target-Kategorie:
Bcl-2 Family,Wnt,beta-catenin
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten